Tuesday, 9 June 2009
Which drugs can cause insomnia?
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Take Medication period, the patients suffer from insomnia, should first take into account the drug-induced insomnia, which is especially common in the elderly. The drugs can lead to insomnia is mainly the following categories:
(1) glycoside drugs: non-time dose, can reduce the renal clearance rate, decreased muscle tone, and some can also be caused by hemodynamic disorders of the rhythm, these side effects can cause insomnia.
(2) diuretic drugs: in particular, combination therapy may be caused by nocturnal polyuria, which disturb sleep; diuretic, the schedule too much potassium, the same rhythm can lead to cardiovascular disorders caused insomnia.
(3) anti-arrhythmic drugs: such as double-isopropyl Disopyramide and procaine amide could affect the quality of sleep.
(4) antihypertensive drugs: such as methyldopa, Rauvolfia element, such as clonidine not only can cause insomnia, can also have a stunning clothes syndrome, causing severe insomnia; improper dosage of antihypertensive drugs, often at night can cause low blood pressure , also can cause insomnia.
(5) β-blockers: β-yin of the drug lag in a lot of agents, in spite of the drugs in the pharmacological nature of the difference between the blood pressure but has a different role; some can cause low blood sugar and induced depression comprehensive symptoms, these side effects can cause insomnia.
(6) Antidepressants: maprotiline and the elderly prunelli commonly used chlorpromazine, imipramine and other antidepressants, can cause insomnia.
(7) anticholinergic drugs: in particular the treatment of Parkinson's disease drugs, as well as tricyclic antidepressants and amitriptyline, can cause irritability at night and insomnia caused by mental disorder.
(8) Amantadine: 16:00 administration, and occasionally can cause insomnia. Taking L-dopa can also occur syndrome insomnia and depression.
(9) pyrazole amine flavanone vinegar: for γ-aminobutyric acid derivatives, may act directly on the cerebral cortex, with the repair, activation, protect nerve cells. Experiment shows that can promote learning ability, delayed hypoxic selection of memory impairment and improve the role of the brain of glucose and energy reserves, improve brain function. However, the drug can not be taken in the evening, otherwise, would have agitated and excited to enter the state, leading to insomnia.
(10) glucocorticoid: such as prednisone, dexamethasone, prednisolone and other drugs, the use of large doses can cause increased excitability of the body and lead to insomnia, hyperhidrosis symptoms.
(11) painkillers efficient: as morphine, meperidine and other drugs, night use, because of its central nervous system stimulant often lead to symptoms such as insomnia.
(12) anti-asthmatic drugs: such as aminophylline, ephedrine and other drugs, night use, because of its central nervous system stimulant often lead to symptoms such as insomnia.
(13) isoniazid: Isoniazid for anti-TB drugs, the use of large doses when excited with the role of the central nervous system, often leads to symptoms such as insomnia.
(14) and stability of drugs: the stability and the amount of inappropriate drugs, and occasionally sleep in the elderly can lead to perversion, that is, during the daytime sedation, and reduce the body, reduce fluid intake, which led to night-time disorder and mental irritability.
In addition to the above drugs, such as anti-cancer drugs, antiepileptic drugs, oral contraceptives, thyroid preparations and certain drugs such as caffeine, can be excited to sleep affect the cerebral cortex.
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